January 2022

Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants

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Key Points Question  What is the association between 3 doses of mRNA COVID-19 vaccine and symptomatic SARS-CoV-2 infection with the Omicron and Delta variants? Findings  In this test-negative case-control analysis that included 70 155 tests from symptomatic adults, the likelihood of vaccination with 3 mRNA vaccine doses (vs unvaccinated) was significantly lower among both Omicron (odds ratio, 0.33) […]

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Traditional Chinese Medicine for COVID-19 Treatment

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The opinion contained in this posting is not of the Midwest College of Oriental Medicine or the administrators of this site. The opinion is of the original author and posted for information purposes.   The decoction, Chinese patent medicine, acupuncture and other characteristic therapy of TCM was comprehensively employed, mainly treated based on syndrome differentiation. Specific

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The ‘Corsi / Rosenthal / Comparetto’ DIY Air Purifier Design

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Several researchers and practitioners, working together and in parallel, have come up with a design for an in-room air purifier which can remove a significant amount of COVID-19 virus from the air. The design involves making a ‘box’ out of four 20″ MERV-13 filters (the ‘sides’ of the box), a 20″ box fan (the ‘top’

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Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection (Long COVID)

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Background Pronounced sex differences in the susceptibility and response to SARS-CoV-2 infection remain poorly understood. Emerging evidence has highlighted the potential importance of autoimmune activation in modulating the acute response and recovery trajectories following SARS-CoV-2 exposure. Given that immune-inflammatory activity can be sex-biased in the setting of severe COVID-19 illness, the aim of the study

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Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harboring both substitutions N501Y and E484K in the spike protein

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SARS-CoV-2 variants have become a major virological, epidemiological and clinical concern, particularly with regard to the risk of escape from vaccine-induced immunity. Here we describe the emergence of a new variant. For twelve SARS-CoV-positive patients living in the same geographical area of southeastern France, qPCR testing that screen for variant-associated mutations showed an atypical combination.

Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harboring both substitutions N501Y and E484K in the spike protein Read More »

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