February 2022

Subvariant May Be More Dangerous Than Omicron: Study

Abstract Soon after the emergence and global spread of a new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron lineage, BA.1 (ref1, 2), another Omicron lineage, BA.2, has initiated outcompeting BA.1. Statistical analysis shows that the effective reproduction number of BA.2 is 1.4-fold higher than that of BA.1. Neutralisation experiments show that the vaccine-induced humoral immunity […]

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Recurrent COVID-19 reinfection and re-emergence of a chronic infection reservoir?, a Brazilian study

Recurrent COVID-19 including evidence of reinfection and enhanced severity in thirty Brazilian healthcare workers Highlights We describe 33 patients with recurrent COVID19 and a positive PCR. Recurrence is associated with working as a healthcare professional, blood-group A, and low IgG response to infection. Evidence from differential virus sequencing between the first and second episode supports de

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Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications

Key Points Question  Among pregnant and postpartum individuals, is SARS-CoV-2 infection associated with increased risk of maternal mortality or serious morbidity from obstetric complications? Findings  In this retrospective cohort study that included 14 104 patients, a composite outcome of maternal death or serious morbidity related to hypertensive disorders of pregnancy, postpartum hemorrhage, or infection other than SARS-CoV-2 occurred

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Disease severity during SARS-COV-2 reinfection: a nationwide study

Highlights SARS-CoV-2 reinfections are associated with a lower risk of death than first infections. Prior infection and immunization both protect against severe disease at reinfection. Age sex and comorbidities are the main risk factors for illness severity at reinfection. Different results in populations at risk of COVID-19 complication and not at risk. Results Deaths reported

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