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Association of SARS-CoV-2 Infection With Serious Maternal Morbidity and Mortality From Obstetric Complications

Leave a Comment / Comorbidity / By

Key Points Question  Among pregnant and postpartum individuals, is SARS-CoV-2 infection associated with increased risk of maternal mortality or serious morbidity from obstetric complications? Findings  In this retrospective cohort study that included 14 104 patients, a composite outcome of maternal death or serious morbidity related to hypertensive disorders of pregnancy, postpartum hemorrhage, or infection other than SARS-CoV-2 occurred […]

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Disease severity during SARS-COV-2 reinfection: a nationwide study

Leave a Comment / Covid Re-infection / By

Highlights SARS-CoV-2 reinfections are associated with a lower risk of death than first infections. Prior infection and immunization both protect against severe disease at reinfection. Age sex and comorbidities are the main risk factors for illness severity at reinfection. Different results in populations at risk of COVID-19 complication and not at risk. Results Deaths reported

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Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants

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Key Points Question  What is the association between 3 doses of mRNA COVID-19 vaccine and symptomatic SARS-CoV-2 infection with the Omicron and Delta variants? Findings  In this test-negative case-control analysis that included 70 155 tests from symptomatic adults, the likelihood of vaccination with 3 mRNA vaccine doses (vs unvaccinated) was significantly lower among both Omicron (odds ratio, 0.33)

Association Between 3 Doses of mRNA COVID-19 Vaccine and Symptomatic Infection Caused by the SARS-CoV-2 Omicron and Delta Variants Read More »

Traditional Chinese Medicine for COVID-19 Treatment

Leave a Comment / Traditional Chinese Medicine / By

The opinion contained in this posting is not of the Midwest College of Oriental Medicine or the administrators of this site. The opinion is of the original author and posted for information purposes.   The decoction, Chinese patent medicine, acupuncture and other characteristic therapy of TCM was comprehensively employed, mainly treated based on syndrome differentiation. Specific

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The ‘Corsi / Rosenthal / Comparetto’ DIY Air Purifier Design

Leave a Comment / DYI Protection / By

Several researchers and practitioners, working together and in parallel, have come up with a design for an in-room air purifier which can remove a significant amount of COVID-19 virus from the air. The design involves making a ‘box’ out of four 20″ MERV-13 filters (the ‘sides’ of the box), a 20″ box fan (the ‘top’

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Paradoxical sex-specific patterns of autoantibody response to SARS-CoV-2 infection (Long COVID)

Leave a Comment / Long COVID / By

Background Pronounced sex differences in the susceptibility and response to SARS-CoV-2 infection remain poorly understood. Emerging evidence has highlighted the potential importance of autoimmune activation in modulating the acute response and recovery trajectories following SARS-CoV-2 exposure. Given that immune-inflammatory activity can be sex-biased in the setting of severe COVID-19 illness, the aim of the study

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Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harboring both substitutions N501Y and E484K in the spike protein

Leave a Comment / Corona Virus Updates / By

SARS-CoV-2 variants have become a major virological, epidemiological and clinical concern, particularly with regard to the risk of escape from vaccine-induced immunity. Here we describe the emergence of a new variant. For twelve SARS-CoV-positive patients living in the same geographical area of southeastern France, qPCR testing that screen for variant-associated mutations showed an atypical combination.

Emergence in Southern France of a new SARS-CoV-2 variant of probably Cameroonian origin harboring both substitutions N501Y and E484K in the spike protein Read More »

SARS-CoV-2 infection and persistence throughout the human body and brain; a pre-peer review article

Leave a Comment / Long COVID / By

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), has well described pulmonary and extrapulmonary manifestations1-3, including multiorgan failure and shock among severe and fatal cases. Some survivors experience Post-Acute Sequelae of SARS-CoV-2 (PASC) – also known as Long COVID—with cardiovascular, pulmonary, and neurological manifestations with or

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NIAID issues new awards to fund “pan-coronavirus” vaccines

Leave a Comment / Vaccine Development / By

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded approximately $36.3 million to three academic institutions to conduct research to develop vaccines to protect against multiple types of coronaviruses and viral variants. The awards are intended to fuel vaccine research for a diverse family of coronaviruses,

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The Cognitive Load of COVID-19 – Harvard Macy Institute Community Blog

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How Does Cognitive Load Theory Relate to COVID-19? Learners in clinical workplaces are at high risk of cognitive overload, and the COVID-19 pandemic compounds this risk. Constantly evolving complex information and changes to workplace practices contribute excessive intrinsic load. Increased demands on time, feelings of uncertainty and anxiety, and negative emotions related to stress introduce

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